Achillefs Kapanidis

My group studies mechanisms and machines of gene expression using single-molecule biophysical methods and biochemistry.

Our main experimental tool is single-molecule fluorescence spectroscopy and imaging, which forms an expanding family of methods that localize single molecules with high precision, measure nanometre-scale distances within molecules and study molecular interactions in real time, both "in vitro" and in living cells. We are actively involved in developing these methods and adding them to novel instruments and biosensing assays. We are particularly interested in "super-resolution" imaging methods that are revolutionizing microscopy by breaking the diffraction limit in optical microscopy and providing us with high-resolution views of our machines in living cells.

For further information, please visit my group research pages or send me an email.